edgeR’s common dispersion

Updated: 2017 September 7th When I was first learning about conducting a differential expression (DE) analysis with RNA-seq data, I found it very difficult to understand the statistical procedures implemented in various R packages that performed the DE analysis. This really bugged me. However, it was not difficult to carry out the analysis, since the…

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The Normal Distribution

Updated 2014 December 19th The normal or Gaussian distribution is commonly occurring continuous probability distribution. The skewness, which is a measure of symmetry (or there lackof), of a normal distribution is zero since the distribution is symmetrical, i.e. it looks the same to the left and right of the centre. Kurtosis can be used to…

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