Computational biology and genomics
Ed Yong asked on Twitter “Explain principal component analysis to a schoolchild in a tweet.” Since I can’t explain PCA eloquently, I found this interesting and wanted to keep a record of the replies for future reference. Here are some of the modified replies, with my favourite first (and the rest in no particular order):…
I labelled only two samples since the text would overlap. Samples 1 to 20 are located near the 16 and samples 21 to 40 near the 37, as expected.
I’ve always wondered what goes on behind the scenes of a Principal Component Analysis (PCA). I found this extremely useful tutorial that explains the key concepts of PCA and shows the step by step calculations. Here, I use R to perform each step of a PCA as per the tutorial. Our dataset visualised on the…