Quantile normalisation in R

Updated 2019 October 11th to explain the index_to_mean function. From Wikipedia: In statistics, quantile normalization is a technique for making two distributions identical in statistical properties. To quantile normalize two or more distributions to each other, without a reference distribution, sort as before, then set to the average (usually, arithmetical mean) of the distributions. So…

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Normalisation methods implemented in edgeR

Updated 2024 August 5th edgeR carries out: Differential expression analysis of RNA-seq expression profiles with biological replication. Implements a range of statistical methodology based on the negative binomial distributions, including empirical Bayes estimation, exact tests, generalized linear models and quasi-likelihood tests. As well as RNA-seq, it be applied to differential signal analysis of other types…

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