Epigenetics

For the past week I’ve been attending the: Karolinska Institutet – RIKEN Joint International Doctoral Course on “Epigenomics: Methods and Applications to Disease and Development” Today is the last day of the course and the course participants have to come up with a proposal that combines epigenetics and its application to a particular disease (our…

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Encyclopedia of DNA elements (ENCODE)

ENCODE is an abbreviation of “Encyclopedia of DNA elements”, a project that aims to discover and define the functional elements encoded in the human genome via multiple technologies. Used in this context, the term “functional elements” is used to denote a discrete region of the genome that encodes a defined product (e.g., protein) or a…

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H3K27Ac

Mainly sourced from Wikipedia but arranged as per my train of thought. Histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation….

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