Computational biology and genomics
Just recently, the genome Aggregation Database (gnomAD) VCF files were available for download: The long-awaited gnomAD VCF is here - sites + frequencies for 123,136 exomes and 15,496 genomes: https://t.co/8puaTvJ45w pic.twitter.com/sxKOEVFDml — Daniel MacArthur (@dgmacarthur) February 27, 2017
Update 2017 May 10th: I realised that this approach doesn't work for all genes, unfortunately. For example, the gene TTN (which is an HGNC approved gene symbol) is associated with 600334, 603689, 604145, 608807, 611705, and 613765 but biomaRt returns an NA. Please refer to an updated post. I was interested in the number of...
A colleague asked me this question: "I'm trying to find a way to find genes that overlap between three datasets. I have used intersect for two dataframes but can't seem to find a solution for three dataframes on google. Do you know any snazzy way of doing that?" I thought using the venn() function from...
In the age of 50,000+ and 60,000+ whole exome catalogues, it's hard to find processed data for a single exome. At least I had trouble trying to find a single VCF file for a single exome from one individual. After searching for a while, I gave up and decided to generate one myself. This post...
I created a basic Shiny app that uses the myvariant package to fetch variant information from MyVariant.info. The variants need to be represented in the format recommended by the Human Genome Variation Society. Once you have your variant of interest in the correct format, just hit "Get variant info!" and the annotations will appear on...
I discovered the superheat package a few days ago and the adjacent plots feature was really attractive. The superheat #rstats package for making heatmaps looks super! I like the adjacent plots https://t.co/KhyA6K6Ap3 — Dave Tang (@davetang31) February 3, 2017
A post on creating a Gantt chart using R; these are good for showing a project timeline in grant applications. The code is adapted from an answer on Stack Overflow. You will need the ggplot2 and reshape2 packages; install them if you haven't already.