Of the RefSeq’s that have CpG islands 1,000 bp upstream, what are the GO terms – part 2?

Using GO.db and GOstats, I obtained the gene list with bona fide CpG islands upstream and conducted a GO enrichment analysis. The choice of the gene universe is again all RefSeq gene models. Enriched Biological Processes include:

1 primary metabolic process
2 branched chain family amino acid metabolic process
3 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4 regulation of transcription, DNA-dependent
5 nitrogen compound metabolic process
6 cellular metabolic process
7 mitotic cell cycle checkpoint
8 nucleobase, nucleoside and nucleotide metabolic process
9 cAMP biosynthetic process
10 G-protein signaling, coupled to cAMP nucleotide second messenger
11 chromatin organization
12 cellular biopolymer metabolic process

Molecular functions:

1 sequence-specific DNA binding
2 transcription factor activity

Cellular components:

Term
1 nucleus
2 membrane-bounded organelle
3 chromosomal part
4 cell
5 intracellular part

Transcription factors more likely to have CpG islands 1,000 bp upstream, and not overlapping the 5' UTR?




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